Às vezes acontece sentirmo-nos felizes por um minuto. Não se deixem levar pelo pânico: é uma questão de segundos e depois passa
@notiun
sexta-feira, setembro 04, 2015
Quevedo, Francisco
Tema: Honra
Aquele que perde a reputação pelos negócios, perde os negócios e a reputação
via @notiun
Aquele que perde a reputação pelos negócios, perde os negócios e a reputação
via @notiun
Shaw, Bernard
Tema: Brincadeiras
A minha forma de brincar é dizer a verdade. É a brincadeira mais engraçada do mundo
via @notiun
A minha forma de brincar é dizer a verdade. É a brincadeira mais engraçada do mundo
via @notiun
Schopenhauer, Arthur
Tema: Insulto
Uma rudeza derrota todo o argumento e eclipsa qualquer espírito; isso se o oponente não tomar parte nela e replicar com outra maior ainda
via @notiun
Uma rudeza derrota todo o argumento e eclipsa qualquer espírito; isso se o oponente não tomar parte nela e replicar com outra maior ainda
via @notiun
The Disabled Teen Who Was Inspired to Get Fit and Change His Lifestyle (18 pics)
Sergei Kutovoy has lost his leg after a car accident in 2013. At the age of 17 he weighed 308 lbs (140 kg). After the crash he decided to go in for sports to change his life once again.
How Your Sleep Position Can Impact Your Brain’s Waste Removal
If you aren’t sleeping in the right position, you could be increasing your odds of developing Alzheimer’s and other neurological disorders later in life.
This shocking conclusion was the result of a study performed by researchers at Stony Brook University when studying the effects of sleeping positions on the removal of brain waste.
Before understanding how the research was conducted and what the findings can mean for your health, it’s first important to understand what brain waste is and how improper removal can negatively impact your health.
Brain Waste and the Devastating Role It Can Play
With the amount of work that your brain performs on a daily basis, it’s no wonder that there will be an excess of waste that requires removal. While our brains don’t have the luxuries of custodians and garbage collectors, they do have their own mechanism for cleaning, and that’s the glymphatic system.
An extensive and organized system of pipes that works to clear brain waste just as the lympathic system clears waste in the rest of the body, this system for waste removal was unknown until 2012 when a group of researchers at the University of Rochester Medical Center made the discovery.
Simply put, brain waste is a combination of amyloids and tau proteins that have overstayed their welcome. The buildup of these improperly functioning proteins has been linked to Alzheimer’s and other neurological disorders and can have truly devastating effects.
The glymphatic system, which functions at all times during the day but which is most active during sleep, is what makes the removal of these proteins possible. Without this system in place, the non-soluble proteins would continue to buildup, leading to a plaque formation within our brain’s cells and wreaking havoc on our nervous system.
How the Research was Conducted
With the use of MRI (magnetic resonance imaging) and contrast dye, the researchers were able to locate the glympathic system and track the movement of its waste-clearing substance in the brains of anesthetized mice.
The mice were then manipulated into lying in one of three different positions — lateral (side), supine (on the back), and prone (on the stomach).
Researchers tracked the rates of waste removal based on these three positions, and the lateral position during sleep had an overwhelming advantage.
What this Discovery Means for You and How You Sleep
While this experiment was performed on mice and has yet to be done on human subjects, there are still some things that we can learn from the study’s conclusion.
The benefits of these findings were best explained by Dr. Nedergaard, a researcher from the University of Rochester and co-author of the study:
“Many types of dementia are linked to sleep disturbances, including difficulties in falling asleep. It is increasing[ly] acknowledged that these sleep disturbances may accelerate memory loss in Alzheimer’s disease. Our finding brings new insight into this topic by showing it is also important what position you sleep in.”
While there is still much research to be done, the conclusion of this study is clear:
“The analysis showed us consistently that glymphatic transport was most efficient in the [side] position when compared to the [back] or [stomach] positions,” said Dr. Benveniste.
The Future of Sleep and Brain Studies
While this new study may not be enough to convince diehard back and stomach sleepers to change their sleep positions, it does lead to future research questions and gives hope to those with a history of Alzheimer’s and similar disorders in their family.
The mysteries of the brain and nervous system are only now beginning to be solved — what this study and similar studies does is prove that each day we are one step closer to a fuller understanding of the human brain and how this knowledge can be used to fight the crippling and fatal effects of neurological diseases.
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20 Amazing Mobile Games To Boost Your Mood And Mind
Over the last few years mobile gaming has become a phenomenal hit and in becoming such a success, it’s introduced new audiences to the brilliance of video games. The pastime once seen as geeky has now been embraced by individuals of all ages, and video games are becoming respected on a widespread cultural level.
To highlight how brilliant mobile games can be, the following 20 have been selected to offer a mixture of modern Indie gems, retro gaming masterpieces, and compellingly innovative new titles. All 20, in one way or another, will boost your mood and mind through a mixture of outright fun, charm, relaxation, and challenges. Take your pick and enjoy!
1. Alto’s Adventure
A perfect game for iOS, Alto’s Adventure is an endless snowboarding odyssey which sees protagonist Alto hurtling down a vast mountain completing missions and performing tricks. It’s at once charming, relaxing, and beautiful, whilst offering a real challenge. As you ski by sunsets and changing weather conditions, you’ll soon realize this is one of the best smartphone games ever made.
2. World of Goo
2D Boy’s physics based puzzle game first appeared on the Wii in 2008. An instant classic, it’s quite brilliant and features a fantastic soundtrack alongside challenging and compelling gameplay. As the player you guide adorable goo balls to safety by building them into increasingly dramatic structures. A must buy.
3. Little Inferno
Remarkably unique, 2D Boy’s endlessly endearing Little Inferno is essentially a puzzle game, of sorts, where players take control of a largely unseen character who burns toys and appliances to keep warm. It may sound simplistic, but 2D Boy’s hilarious use of language mixes with a poignant atmosphere to create an unforgettable experience.
4. Thomas Was Alone
An Indie classic, Thomas Was Alone is an amusing and poignant narrative based puzzle game. The winner of numerous BAFTA awards, and featuring narration from Danny Wallace, the player guides a selection of sentient shapes on a journey of self-discovery.
5. BIT. TRIP RUN!
Known as Runner 2 on consoles, this endless runner sees the player star as Commander Video. It’s a musical game involving the need for perfect timing, which allows you to traverse increasingly complex levels. The absolutely stunning soundtrack and relentless action will leave you thrilled, making this another Indie classic. Don’t forget your earphones!
6. Monument Valley
Clearly inspired by graphic artist M. C. Escher’s work, Monument Valley is an award winning puzzle game which is breathtaking to look at and a challenging experience. Guide Princess Ida through levels and enjoy the beautiful graphics along the way.
7. Secret of Mana
A SNES classic from 1993, Square Enix’s (back then known as Squaresoft) excellent RPG has made a strong transition to iOS. The control system works well and you’ll be immersed in this charming world with its colorful graphics, outstanding soundtrack, and well structured story.
8. Chrono Trigger
Another SNES classic, this time from 1995, Chrono Trigger is an RPG considered one of the best games of all time. Renowned for its excellent story-line and compelling gameplay, it was a tour de force for Square Enix 20 years ago and remains an enduring classic.
9. Final Fantasy VI
Released in 1994 on the SNES, Final Fantasy VI is another of Square Enix’s RPG masterpieces. It costs a bit ($15.99) but it is arguably one of the best games of all time, and at a sprightly 512MB for a game of this quality you can’t go wrong.
10. Final Fantasy VII
One of the best games of all time, this legendary RPG first appeared on the PlayStation in 1997. It’s a beautiful, charming, and magical game with a highly emotional narrative. It’s just launched for iOS (August 2015), but the downside is it takes up some 1.63GB. On the upside, the game is a masterpiece!
11. Limbo
The critically acclaimed Limbo is about a boy who heads off to discover his sister’s fate. It’s a puzzle and platform based game with a dark, melancholic edge, but it does have an enigmatic beauty about it and makes for a captivating experience.
12. BADLAND
One of the most peculiar games on this list, BADLAND is an action adventure game involving a large amount of atmospheric flying. The trick is to survive the brutal environments, and whilst you do enjoy the beautiful scenery and sound effects!
13. Superbrothers: Sword & Sworcery
Apple noted this game as a “landmark title” – it’s an action adventure game with a mix of retro graphics and classic gameplay. As the protagonist you use your sword to perform “sworcery” in order to solve musical mysteries. It’s very charming!
14. Vainglory
This MOBA (multiplayer online battle arena) is one of the best multiplayer options for iOS. Simply put, two opposing teams do battle to destroy the enemy base. It’s free to play, but if you want to upgrade there are in app purchases – if you’re willing to commit to Vainglory then it’s worth it.
15. Blek
This award winning puzzle game is simple, intuitive, incredibly challenging, but always beautiful. Its gesture based puzzle solving starts off easy enough, but soon becomes difficult.
16. 80 Days
80 Days is interactive storytelling with a steampunk twist! Considered one of the best iOS games of all time, this is essentially an interactive novel and it’s quite a riveting experience. You’ll find strategy, resource management, and a dose of adventure all rolled into one.
17. Year Walk
Loosely based on the Swedish tradition Arsgång (a form of divination), Year Walk is an elegant adventure/puzzle game which plays out like an excellent psychological thriller film. It’s a brief experience, but it’s an intelligently crafted and thrilling little adventure.
18. Bastion
This award winning action RPG made its name on the PC and is now a universal app on iOS. Yet another title boasting a brilliant soundtrack, Bastion’s mix of compelling action and adventure works wonders and immerses you into the experience.
19. Odd Bot Out
In this adorable puzzle game you must help Odd escape a robot factory using building blocks, electricity, and physics. It’ll test your mental abilities whilst offering a unique visual treat – well worth the budget price.
20. Does Not Commute
Does Not Commute is a strategic driving game described as a “temporal paradox” – you have yourself to blame if your progress is hindered. You take control of commuters and guide them along their way, but each path you take can interfere with your next charge. It’s free to download – try it out and, if you like it, upgrade for save spots!
Featured photo credit: Ice/Snowman via builtbysnowman.com
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